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The mixture was incubated at 37 C for 1 h, then at 95 C for 10 min, and finally cooled at 4 C

In addition, tumor cells in the bone metastatic niche hijacked VCAM1 + CD163 + CCR3 + macrophages of the erythroblastic islands, which usually supply iron to erythroblasts, disrupting iron homeostasis within the hematopoietic niche, impairing erythropoiesis and contributing to cancer-associated anemia [75]

Redmon, J

It has many important functions which are discussed below

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