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Upon entry, these cells then exponentiate cytokine release and sustain a pro-inflammatory milieu in the CNS, in part via upregulation of NLRP3 inflammasome activity (discussed in Sect

Both are highly effective, but they target different fitness goals

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4.2.2 Cholecystokinin CCK, a gut-brain peptide hormone predominantly secreted by duodenal and jejunal I-cells in response to lipids and proteins, is a key satiety signaling triad member alongside GLP-1 and PYY (Lorenz and Goldman, 1982)