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Thus, we envision that clinical trials in humans may start by testing whether ferroptosis inhibitors protect from ischemiareperfusion kidney injury during transplantation: this is a predictable for of AKI that allows ex vivo therapeutic maneuvers

Otherwise, GSH depletion results in increased -Gcs, leading to accumulation of pyroglutamic acid (76)

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Guiyun Jin, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers