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CD4 + Teff cells differentiate into functionally distinct subsets in different cytokine environment: Th1, Th2, Th9, Th17, etc

Recently, FASN and ACC were reported to be upregulated by novel mechanisms in CRC

doi: 10.1186/s12890-017-0517-0 19 WangTLafuseWPZwillingBS

We show evidence that distinct importin conformers bind to and are stabilized by IBB, xIBB, Ran-GTP, Ran-GTP:RanBP1, and Ran-GDP:RanBP1, leading to structurally different solenoids