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J Clin Invest (1994) 94(4):14905

3, FAO, 2013): 100 x (mg of digestible dietary indispensable amino acid in 1 g of the dietary protein / mg of the same dietary indispensable amino acid in 1 g of the reference protein) DIAAS scores are not truncated at 100%

It leads to changes in the structure of skin matrix proteins, such as collagen and elastin, and consequently, to loss of skin elasticity and firmness, the formation of wrinkles, and pigmentation disorders (116118)

Finally, the effectiveness and feasibility of targeting APOA4 and PCSK9 in clinical treatment remain to be demonstrated

Data extraction and quality assessment The following data were extracted from the included RCTs: authors, year of publication, country of origin, sample size, duration of follow-up, route of L-carnitine supplementation, dose, mean age and proportion of male participants