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Nature medicine , 28 (6), 12881296

Silica exposure has been linked with various ADs including SLE, RA, and systemic sclerosis ( Lupus-prone NZ-2410 mice exposed to silica exhibited increased autoantibodies, circulating immune complex, renal deposits of C3, and proteinuria ( Smoking Linking smoking with autoimmunity, especially its role in the pathogenesis of ADs has been a subject of great interest ( IL-7R + CD8 + T cells resulting in the release of survivin, and that potentially presents a new mechanism for smoke-mediated RA pathogenesis ( Smoking influences intestinal microbiome by altering its composition

Estrogen replacement therapies or estrogen-mimetic drugs could be explored as potential treatment options for male patients or for postmenopausal female patients who may no longer benefit from their estrogen levels

p 0.05), highlighted breed-specific metabolic and structural differences (Fig

The yield of MW hydrolysis by NEC was 35.92% (w/w), and the degree of hydrolysis was 15.10%