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These findings are of interest to clinicians as melatonin protects against mitochondrial dysfunction, apoptosis, and dopaminergic degeneration, which are considered to contribute to several psychosomatic manifestations in METH abusers

While defects in carnitine biosynthesis do not result in carnitine deficiency, severe plasma and intracellular carnitine depletion occurs due to defects in carnitine transport [5]

This study was approved by the Ethics Committee of Womens Hospital School of Medicine Zhejiang University

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Energy metabolism, tissue determinants and cellular corollaries