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Many, but not all of these cases, have shown a positive response to treatment with vitamin B12, based on improvements in abnormal metabolite levels and clinical indices (Stabler et al., 1990)

RBCs, red blood cells

The effectiveness of D-methionine in this connection brings back to mind the early studies of Rose who used DL-methionine in his early balance studies which led to the RDA recommendations, again suggesting a significant role for the SAA, beyond that of protein synthesis

This highlights the importance of identifying preventive strategies to mitigate the risks associated with the use of these agents (Table 1)

Response varies between individuals