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Description

NRF2 signaling pathway The NRF2 antioxidant response pathway is a major defensive system whose impairment contributes to PD

(para)sympathetic nervous system function & neuroendocrine signaling [107]]

141, pp

Moreover, MSU relies on ITGB1 on the surface of macrophages to activate the inflammatory signaling pathway, which suggests that targeting and inhibiting integrins on the surface of macrophages to inhibit inflammation in MSU-induced inflammatory complications is one of the research directions for precision therapy