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First, due to the lack of a sedentary control group in the establishment of the mouse models of EIF, the results of biochemical factors in our study should be cautiously considered

In practice, activity pacing is guided by several key principles: (i) Understanding Energy Limits: Patients learn to recognize their personal energy thresholds, identify early signs of overexertion, and abstain from activities that exceed these limits [173]

48 For patients with established heart disease, studies have shown that aggressive treatment to reduce LDL-C levels below 100 mg/dL (2.6 mmol/L) or even lower is effective in the stabilization and sometimes regression of plaques

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