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Kim DJ, Tremblay ML, Digiovanni J

[10] [11] Craniosynostosis [edit] Mutations in IGF1R have been associated with craniosynostosis

Furthermore, 15-deoxy-12,14-prostaglandin J2 (15d-PGJ2) is generated from arachidonic acid during inflammation and 2-trans-hexadecenal (2-HD) is produced during sphingolipid metabolism which promotes apoptosis (Wang et al., 2014)