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Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

*Correspondence: Ruchira Salunkhe, [email protected] This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Humans have sought substances to improve our cognitive function for centuries, from ancient civilizations using hallucinogens in an attempt to raise their consciousness to commune with their gods, to the rise of coffee, to the more recent development of drugs such as stimulants and glutamate activators

However, some subjects may experience moderate stomach upset [15]