glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of A glutathione-triggered precision explosive system

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of A glutathione-triggered precision explosive system
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SKU: 85438404997
Price: 27.00 USD
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Rating: 4.882000000000001 (19 reviews)

A glutathione triggered precision explosive system for improving tumor chemosensitivity Nano Research Springer Nature Link PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis A GSH Activatable Theranostic Prodrug Based on Photoinduced Electron Transfer for Cancer Fluorescence Imaging and Therapy Glutathione responsive prodrug conjugates for image guided combination in cancer therapy ScienceDirect Construction of glutathione responsive paclitaxel prodrug nanoparticles for image guided targeted delivery and breast cancer therapy RSC Advances (RSC Publishing) DOI:10.1039 D4RA00610K

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Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm