glutathione s-transferases resistance Frontiers Impact of the GSTe2 glutathione

Bergsten, E

A gene ontology enrichment analysis (ToxoDB) of the 249 proteins decreased in abundance indicated that proteins involved in translation (59 proteins, 6.31-fold enrichment, p-value 2.5 x 10 -33 ), ribosome biogenesis (10 proteins, 3.93-fold enrichment, p-value 1.78 X 10 -4 ), DNA replication (9 proteins, 4.39-fold enrichment, p-value 1.59 x 10 - 4 ), DNA replication initiation (6 proteins, 16.26-fold enrichment, p-value 3.34 x 10 -7 ) and DNA dependent DNA replication (6 proteins, 8.61-fold enrichment, p-value 3.73 x 10 -5 ) were significantly enriched in our dataset

In some embodiments, the cell is a macrophage subtype, e.g., a macrophage subtype described herein

1996 Sep;36(18):3003-9

Baseline demographic data of the study groups are displayed in Table 1