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This work was supported by the NIH (RC2DK129964 to A.Y.T., R01-DC006982 to L.L

The well water is easily contaminated by surface water conditions, this kind of yellow or cloudy well water can no longer be drunk

Swart PJ, Hirano T, Kuipers ME, Ito Y, Smith C, Hashida M, et al

With oral supplementation, we are limited in how high we can dose nutrients due to risk of gastric irritation and other unpleasant side effects

however, dedicated cardiovascular outcome trial (CVOT) data have not yet been published, and cardiovascular benefit has not been demonstrated Phase 3 trials are ongoing