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The role of blood branched chain amino acids (BCAA) in regulating neurotransmitter profiles under disease conditions also warrant discussion

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Gachon and Mesquida (2020) found that collagen fibrils from adult rat tail tendons treated with glutaraldehyde do not show normal strain-stiffening and strain-softening behavior ( i.e ., excessive crosslinking causes fibrils to continue stiffening through higher strains, resulting in a more brittle behavior during fracture), differently from untreated control fibrils that exhibit strain-stiffening and strain-softening ( i.e ., fibrils initially straighten in response to strain before the fibrils themselves undergo softening at higher strains)

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306 In addition, miR-19b-3p contributes to the radio-resistance of NPC by activating the TNFAIP3/NF-B axis, and miR-19b-3p is a determinant of NPC radio-response and might serve as a potential therapeutic target in NPC treatment