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From Krebs to clinic: glutamine metabolism to cancer therapy

AMT lacks receptor specificity, which increases the off-target distribution 118,119

Because sulfoxide metabolites are more potent nephrotoxicants than their parent S -conjugates, more research is needed on the extent of formation of S -(1,2-dichlorovinyl)-L-cysteine and N -acetyl- S -(1,2-dichlorovinyl)-L-cysteine sulfoxides by human tissues (liver and kidney), the extent to which these reactions occur in vivo, the enzymes involved, and their interindividual variability, including the role of genetic polymorphisms

While these legal requirements protect end-users, they can meaningfully constrain market expansion

Its ability to reduce oxidative stress, bolster immune function, and manage inflammation also has a significant impact on overall health and disease progression