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10.1016/j.phymed.2014.11.019 126 IvanovE.AkhmetshinaM.ErdiakovA.GavrilovaS

72 Interestingly, several ASD animal models, including Fmrp -mutant, 167 Mecp2 -mutant, 113 Tsc1/2 -mutant, 226 Pten -mutant, 227 Shank3 -knockout, 211,228 Nlgn3 -knockout 229 and 16p11.2-knockout models, 26 have shown dysregulation of mGluRs and abnormal mGluR-dependent LTD

These mechanisms, combined with enhanced immunity, likely contributed to the absence of bacterial growth in the -LA group

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