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Polyphenols in inner ear neurobiology, health and disease: from bench to clinics

Previous studies have demonstrated that hydrogen gas can inhibit the formation of nitrotyrosine (Zhang et al., 2016), a detectable marker for the indirect measurement of ONOO (Wu et al., 2018), suggesting that hydrogen gas may exert its antioxidant effects by inhibiting ONOO

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Specifically, in Nrf2 knockout SW480/HCT116 cells, we will analyze differentially expressed genes associated with iron metabolism (e.g., TFR1, FTH1) and LPO (e.g., ACSL4, LOXs)

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