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PMID: 41462498 PLoS PathogThe B169L protein of African swine fever virus functions as a viroporin that activates the calcium-mediated inflammasome

Using in vitro liver models, we showed that these thiomethyl metabolites are directly linked to the elimination of the hepatotoxic NAPQI metabolites since S-CH 3 -APAP-S and SO-CH 3 -APAP-S are formed at high levels after exposure to NAQPI-derived metabolites (glutathione, cysteine, and mercapturate conjugates) in both primary human hepatocytes and HRG cells

Vitamin C : regenerates glutathione, stimulates collagen synthesis

4.9 Ferroptosis in Huntingtons disease HD is an autosomal dominant neurodegenerative disorder caused by CAG repeat expansions in the HTT gene, which encodes mutant huntingtin (mHTT) proteins containing elongated polyglutamine (polyQ) tracts

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