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10.4088/JCP.21r14328 16 ArnoldF

Nicotinamide mononucleotide prevents retinal dysfunction in a mouse model of retinal ischemia/reperfusion injury

Vitamin B12 is known to be non-toxic even in high doses

Treatment protocols can vary depending on the prescriber and the patient, but there are usually some commonalities despite the variables

30 The activation of genes responsible for antioxidant defense (e.g., the glutathione (GSH) system, 8 coenzyme Q10 (CoQ10) system, 31,32 and the nuclear factor, erythroid 2-like 2 (NFE2L2, also known as NRF2) transcription pathway 33 ) and membrane repair (e.g., the endosomal sorting complexes required for transport (ESCRT)-III pathway 34 ) limit membrane damage during ferroptosis (Fig