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Tumor-derived lactate creates a favorable niche for tumor via supplying energy source for tumor and modulating the tumor microenvironment

Sharp M, Wilson J, Stefan M, Gheith R, Lowery R, Ottinger C, et al

MBio 6, e01453-15

BC-secreted CCL2 recruits CCR2 + inflammatory monocytes to the LPMN, fostering metastatic progression [143]

J Immunol (2010) 184(7):37808.10.4049/jimmunol.0901384 126 NouaillesGDayTAKuhlmannSLoeweDDorhoiAGamradtPet alImpact of inducible co-stimulatory molecule (ICOS) on T-cell responses and protection against Mycobacterium tuberculosis infection