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doi: 10.1104/pp.16.00273 177 VanderauweraS.VandenbrouckeK.InzA.Van De CotteB.MhlenbockP.De RyckeR.et al

Generation of 3HAHMOX2 KI cells Knock-in at the HMOX2 genome locus was performed using the PITCh method, as previously described 63

Rather than acting through a single receptor or pathway, the peptide is thought to engage in a distributed mode of action, subtly shifting gene expression patterns toward a state associated with maintenance and adaptation