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In summary, engineered extracellular vesicles, through precise functional design, show significant advantages in improving targeting, optimizing drug loading, and enhancing therapeutic effects, providing new technological pathways for the treatment of intervertebral disc degeneration

Gonzalez-Bohorquez, D

Moreover, the immunogenicity response of GX-G3 was lower in monkeys than in rats, which was relevant to show less inhibition of toxicokinetic profiles in monkeys, at least 1 mg/kg administrated group, compared to rats

doi: 10.1111/ajd.12290 [DOI] [PubMed] [Google Scholar] 17.Neagu N, Conforti C, Agozzino M, et al

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