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Akiyoshi et al [7] concentrated the fecal material by centrifugation at 4000 g for 10-15 min

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These findings position serum GM as a prognostic biomarker for IPA in AECOPD

Examples are accelerated glycolytic fluxes, ATP generation, a backup and diversion of glycolytic intermediates, the biosynthesis of nucleotides, the production of non-essential amino acids, lipids and hexosamines, maintenance of cellular redox homeostasis, low ROS formation, inhibition of pyruvate entry into mitochondria, lactate accumulation, stimulating sustained proliferation and suppression of anti-tumor immunity, and extracellular acidosis, which accelerates malignant progression and drives resistance to conventional therapies (Vaupel and Multhoff, 2021)

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