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Unlike cryotherapy, which may leave scars, or surgical excision, which can be painful, PDT works locally on damaged skin cells with minimal trauma to surrounding tissue

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In contrast, Syk kinases are activated through the interaction of their tandem Src homology 2 domains with ITAM domains, 374 primarily regulating the activation of neutrophils by ICs through FcR, 375 essential against various pathogens including bacteria and fungi

Carbomer was used in place of HPMC as polymer / gelling agent and placebo transdermal gels are prepared as provided in comparative example 2

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