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The results indicate that lead poisoning was characterized by high blood lead concentration and low -ALAD activity, induction of oxidative stress with high lipid peroxidation and low total antioxidant capacity (TAC), as well as a higher degree of PS externalization

10.1161/JAHA.120.020180 150 Tom NijenhuisVallonV.Annemietevan der KempW

According to the World Health Organization (WHO), a strong immune system is fundamental in preventing and fighting infections, and nutritional status, including amino acid availability, significantly impacts immune competence

The situation is further complicated by the fact that even healthy individuals show a decline of oxidative phosphorylation with age, perhaps due to accumulating damage in mtDNA

To discriminate against such bias, we excluded females in our first rigorous cohort