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Subtracting this 0.5 g of reabsorbed B12 from the 1.5 g that normalizes blood parameters results in a requirement of 1.0 g absorbed per day (for those without pernicious anemia)

Some research suggests that low vitamin B12 combined with high folic acid intake may be associated with elevated homocysteine and methylmalonic acid levels

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For someone with low B12 levels or an absorption issue, treatment may support: Healthier red blood cell production Normal nerve function Improved energy related to correcting a deficiency Better concentration Reduced weakness Overall nutritional wellness Some patients notice a difference within hours or days