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Expected efficacy and side effects Common side effects of semaglutide with glycine may include nausea, diarrhea, constipation, abdominal discomfort, and heartburn

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According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, weight loss medications should be offered as chronic treatment along with lifestyle modifications to patients with obesity when the potential benefits outweigh the risks