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Thus, it is urgent to advance our knowledge regarding subretinal fibrosis and its pathogenic mechanisms to develop alternative therapeutic options

Over time, these factors can contribute to the deterioration of the epidermis, causing it to become darker and develop a rough texture

In conclusion, in a meta-analysis of four studies, which included 259 AD patients and 307 healthy controls, it was observed that AD patients had significantly lower serum vitamin E levels than the control group (standardized mean difference: -1.08, 95% CI: 1.80 to 0.36) (81)

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