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Verapamil and drugs such as vincristine however, when bound in zone D, probably interact with MRP1 in different ways, as already suggested 8 and stimulate GSH uptake also in different ways

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If a biological product was previously licensed under a different regulatory pathway (e.g., as a biologics license application converted from an NDA during the transition of protein products to biologics regulation), the first licensure date may significantly predate the current BLA holders commercial launch

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