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Frataxin deficiency in the mitochondrion leads to ISC failure and ROS generation

Always moisturize and wear sunscreen if applying on exposed skin

Downregulation of solute carrier family 7 member 11 (SLC7A11), a component of System Xc-, has been shown to induce ferroptosis (YAO et al., 2021), resulting in an imbalance in the Gln metabolism pathway

For instance, Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (in PD, AD, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (PD), is a stress marker (temporal lobe epilepsy), and also protects cells from cerebral ischemic injury

Encapsulating or conjugating sodium channel blockers into nanocarriers allows for enhanced drug bioavailability, solubility, and target-specific delivery, resulting in better therapeutic effects