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doi: 10.3390/ijms222312960 180 KimJBWrightHMWrightMSpiegelmanBM

(1996) Nature 384: 432 and Cell (1996) 84: 769

Vitamin B 1 is essential for the health of the brain and nerve tissue

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If GI symptoms are severe or persistent beyond three weeks at any given dose, consult your healthcare provider rather than pushing to the next escalation level