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Introduction Glutathione (GSH) is a tripeptide (Glu-Cys-Gly) that is the major low molecular mass thiol in mammals

Results Selective autophagy is necessary for Stat92E but not for JNK pathway activation To better understand nervous system adaptation after injury, we investigated whether autophagy impacts signaling pathways in glia

Oral Supplements Oral glutathione supplements are widely available, but their effectiveness can be limited by digestive breakdown

This bifunctional nature of GST allows it to participate in detoxification reactions by facilitating the conjugation of glutathione to a wide range of substrates

This postulated mechanism of action explains why parasites treated with auranofin accumulate ROS (4)