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For antidepressants, as when starting a benzodiazepine, an opioid, or a corticosteroid, this includes understanding that it may be very difficult to stop, and that long-lasting withdrawal symptoms are possible

However, once uncontrolled oxidative stress occurs and cytokines are overproduced, not only can the inflammatory state of the lungs be exacerbated, but more ROS will continue to be produced, worsening the situation (Figure 3)