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One of the earliest studies demonstrating ferroptosis in PD model animals came from experiments using the MPTP model (Do Van et al., 2014)

Saudi J Biol Sci 25:16391647

Therefore, the inhibition of nucleotide biosynthesis by pharmacological therapies may be an effective approach for eradicating specific tumors, such as antifolates and nucleosides that have been used in the treatment of cancer for a number of years (132)

Open field Motor function and signs of anxious behavior were evaluated through open field testing

Although not usually needed, we can even suggest pharmacogenomic testing to determine how they metabolize medication