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Drug repositioning represents an alternative approach to mitigate for safety issues (Sisignano et al., 2016b)

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Holst and Williamson [99] proposed that in vitro plant antioxidant assessment studies be driven by in vivo results, and not vice versa

Treatment with the ferroptosis inhibitor Fer-1 reduced myocardial hypertrophy and pathological remodeling [237], underscoring the role of ferroptosis in hypertensive cardiac injury