glutathione deficiency paracetamol Fasting depletes Glutathione, turning "safe" doses into a liver-toxic emergency. Don't let a therapeutic dose become a lethal one. See the safety protocols on BMJ Best Practice via bio. 🔍 #MedEd # Too much paracetamol = dangerous

Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem Acetaminophen Toxicity: OPPOSITE EFFECTS OF TWO FORMS OF GLUTATHIONE PEROXIDASE ScienceDirect Mind the Anion Gap: 5 Oxoproline Induced High Anion Gap Metabolic Acidosis in End Stage Renal Disease Cureus The competitive relationship between paracetamol sulfation and Download Scientific Diagram The diagram illustrates the process of paracetamol metabolism, which Download Scientific Diagram

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