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coli infection induced local changes in the peritoneum alone, not in the plasma or lungs ( Above all, advanced host types of machinery protect cells by detecting and preventing damage due to intrinsic and exogenous inferior substances, such as oxidative stress and toxins ( Keap1-Nrf2 Signaling Pathway The Keap1-Nrf2 regulatory pathway is a key mechanism for preventing cell damage by detecting intrinsic and exogenous stresses, such as oxidative stress, chemotherapy, and radiation, regulating gene expression to modulate various subsequent antioxidant functions ( Figure 2 ) ( via activation of the Keap1-Nrf2 signaling cascade (95)

Weber AG, Chau AS, Egeblad M, Barnes BJ, Janowitz T

We hypothesized that a secreted protein between cells contributes to the loss of neurons in PD by affecting the sensitivity of dopaminergic neurons to ferroptosis

doi: 10.3389/fcimb.2023.1290914 111 GhaniRChrysostomouDRobertsLAPandiarajaMMarchesiJRMullishBH

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