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Both that AT 1 and AT 2 receptor subtypes are 7-transmembrane domain G-protein coupled receptors with molecular weights of 40-42 kDa

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As the pluripotency genes, such as Nanog , also show fluctuating expression in ESCs (Chambers et al., 2007), could this imply that the transcription of the Sox2 gene also fluctuates and causes oscillatory expression of developmental TFs without leading to differentiation