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Researchers used Ce6 (photosensitizer), V-9302, and BMS-1 (PD-1/PD-L1 inhibitor) to develop a photodynamic immunostimulant BVC with good stability and high drug delivery efficiency

Here we review receptor biology and coactivator coupling, the pharmacology of SLU-PP-332 in cells and animals, dosing paradigms and route considerations used in published studies, translational biomarkers and experimental endpoints, context-dependent risks and unknowns, and practical guidance for nonclinical study design

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If the vial was already partially through its room temperature budget from previous exposures, account for the cumulative total

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