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Researchers recruited 231 healthy adults with no dementia or mild cognitive impairment through the Brain Aging Network for Cognitive Health, average age 71, median B12 concentration around 414.8 pmol/L, comfortably inside the normal range

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Side Effects to Know Reported side effects in patient use are generally mild and self-limiting: Mild injection site irritation or redness Occasional fatigue in the first week Rare nausea or headache Transient flushing Serious adverse events have not been commonly reported in the supervised clinical context, but long-term human safety data is still being gathered