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Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGF signalling and EMT

However, combining with other SIRT1 activators (resveratrol, pterostilbene) or AMPK activators (metformin, berberine) has not been systematically studied

Its major role is as an antioxidant (1) , involved in the elimination of free radicals and the detoxification of the liver through liver glutathione

[DOI] [PubMed] [Google Scholar] 61.Ito M., Yang Z., Andl T., Cui C., Kim N., Millar S.E., Cotsarelis G

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