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p = 0.0089)

SEQ ID NO:74) using the Proceryon suite of software (Proceryon Biosciences, Inc., N.Y., N.Y.)

That this was not a cell culture-specific event was confirmed by its occurrence in leukemic patients undergoing treatment with high-dose 1-beta-D-arabinofuranosylcytosine and hydroxyurea

Oxid Med Cell Longev 2018:117

So, RBCs cannot face oxidative stress because of the insufficient glutathione synthesis and the inefficient pentose phosphate pathway to produce NADPH, which leads to the irreversible oxidation of key structural and functional proteins such as hemoglobin, band 3, and peroxiredoxin 2 (Bayer et al., 2015