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Description

In retinal endothelial cells, high glucose results in mitochondrial dysfunction via mitochondrial Dynamin-related protein 1 (Drp1)-mediated mitochondrial fission (Zhang et al., 2022)

J Pathol (1996) 180(2):1529

doi: 10.1146/annurev.physiol.69.031905.164337 20 ZhangDLGhoshMCRouaultTA

A.LiuZ.GouldJ.MccarrenP.HirschmanJ

The invention also features receptor-specific antibodies which both prevent ligand binding and receptor activation as well as antibodies that recognize the receptor-ligand complex, and, preferably, do not specifically recognize the unbound receptor or the unbound ligand