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Description

In this context, regulated apoptosis and subsequent extrusion of apoptotic cells contribute to maintaining epithelial cell numbers and barrier integrity

100 NencioniL.IuvaraA.AquilanoK.CirioloM

8,9,10 Here in this review, we highlight those known and yet unexploited key molecular and signaling pathways, particularly the inflammatory, epigenetic, and metabolic aspects that link cell senescence and organismal ageing (Fig