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Two forms of B12 that are active in human metabolism are methylcobalamin and 5-deoxyadenosylcobalamin (methylated vitamins)

This steadier drug level also means that GI side effects, when they occur, tend to be milder with sublingual dosing

FIGURE 6 Pearson correlation was used to analyze the relationships between differential metabolites and metabolic pathways (Pearson correlation coefficient (r) and p BH are provided in Supplementary Tables S4, S5)