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Yes, high-dose oral Vitamin B12 pills (usually 1000 to 2000 micrograms per day) are a highly effective alternative to lifelong intramuscular injections for most people with autoimmune gastritis or pernicious anemia [1] [2]

Am J Cardiol 77:200202 Spies M, Wolf SE, Barrow RE et al (2002) Modulation of types I and II acute phase reactants with insulin-like growth factor-1/binding protein-3 complex in severely burned children

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Pharmacokinetic studies in rats demonstrated an oral bioavailability of 38.4%, with a mean Cmax of 2,252 ng/mL and terminal elimination half-lives of 3.80 1.10 hours (IV) and 6.90 1.20 hours (oral) (Awosemo et al., 2021)