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Forward genetic screens for mutants defective in transgenerational inheritance indicated an essential role of the ubiquitin ligase EBAX-1/ZSWIM8 and the destabilization of clustered microRNAs of the miR-2235/miR-35 family for transgenerational memory

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1 In a retrospective chart review of 542 patients clinically diagnosed with gout, 85% of the X rays were read as normal. However, X-rays can help rule out alternative diagnoses for joint pain and swelling such as fracture