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This anatomical distinction underlies the concept of dual serotoninergic systems: over 90% of the bodys 5-HT is produced in the periphery (primarily in the gut), while CNS-derived 5-HT acts as a key neurotransmitter (Loh et al., 2024)

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In contrast, glucose does not appear to be a primary carbon source used by meningococci in the intracellular environment

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